![]() Once thought to be interchangeable terms, TTP and HUS have distinctly different mechanisms. In recent years, our understanding of pathophysiology has improved considerably. ![]() 3 Regardless of the etiology, thrombotic microangiopathy is a hematologic emergency that requires prompt treatment. The incidence of TTP in adults is about 3 per 1 000 000, 2 and the incidence of HUS in children is about 3 per 100 000. Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are primary forms of thrombotic microangiopathies. It is a process of red blood cell destruction within the microvasculature accompanied by thrombocytopenia due to platelet activation and consumption. Microangiopathic hemolytic anemia is the hallmark of thrombotic microangiopathy. Primary care or emergency department physicians are often the first point of contact however, once the diagnosis is suspected, urgent referral is needed to a specialty service (e.g., hematology or nephrology) that can provide plasma exchange. Presenting symptoms may be nonspecific, but basic laboratory tests reveal a specific constellation of thrombocytopenia and anemia with red blood cell fragmentation on the blood film and evidence of hemolysis. 1 Though rare, thrombotic microangiopathies are life-threatening conditions that require urgent management. Thrombotic microangiopathies are a group of disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia and microthrombi leading to ischemic tissue injury. ![]()
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![]() ![]() A year later, Briony (Romola Garai), now eighteen, also arrives in London to start working as a nurse to support the war effort. ![]() ![]() Robbie is able to reconnect with Cecilia before he is shipped off to France, and lives only to be able to head back to London to be with Cecilia and make up for the missing four years they could not spend together due to Briony's actions. Based on two incidents she saw between Cecilia and Robbie (one only from afar), on reading a private letter Robbie wrote to Cecilia, and on her own feelings for Robbie, Briony told some truths and half-truths about Robbie which resulted in this turn in his life. But then thirteen-year-old aspiring writer Briony also had a crush on the older Robbie. Robbie and Cecilia were just getting to the stage of their lives of being able to confess their true love for each other. As such, he grew up with the three Tallis children: son Leon (Patrick Kennedy), and daughters Cecilia (Keira Knightley) and Briony (Saoirse Ronan). A stint in the army is not where his life was headed, which took a radical turn four years earlier at the Tallis estate where he grew up as his mother worked as the Tallis' live-in housekeeper. In 1939, Robbie Turner (James McAvoy) is a Private in the British Army, he and his battalion who are heading to France to fight in the war. ![]() ![]() Dante, however, cannot distinguish whether it is a man or a shadow. While Dante goes backward to the forest, he sees a human figure and turns to it for help. The three beasts are allegories of three different sins: the leopard represents lust, the lion pride, and the wolf represents avarice. They force Dante back into the dark forest. While he seeks a way out of the forest, he meets three beasts: a leopard, a lion, and a wolf. The events of the Divine Comedy are set around 1300 because Dante was born in 1265 and rumored to be in the middle of his earthly life, which at that time was considered to be about seventy years.ĭante imagined a scary forest as a metaphor for sin. He did not realize what happened because his soul was sleepy and numb. It is horrible, tangled, and wild, and only the memory of it makes Dante scared. Inferno 1 is the first canto in Dante’s Divine Comedy and perhaps the most famous of the epic poem.ĭante, author and protagonist of the poem, is in the middle of the journey of his life, in a dark forest. ![]() I found myself within a forest dark, Langdon thought, recalling the ominous first canto of Dante’s masterwork, for the straightforward pathway had been lost. ![]() ![]() ![]() This sage advice will prove useful and entertaining to anyone charged with the sometimes perilous task of improving the writing of others. ![]() The Subversive Copy Editor brings a refreshingly levelheaded approach to the classic battle between writers and editors. Saller maintains that through carefulness, transparency, and flexibility, editors can build trust and cooperation with writers. The revised content reflects today's publishing practices while retaining the self-deprecating tone and sharp humor that helped make the first edition so popular. She expands her advice for writers on formatting manuscripts for publication, on self-editing, and on how not to be "difficult." Saller's own gaffes provide firsthand (and sometimes humorous) examples of exactly what not to do. In this second edition, Saller adds new chapters, on the dangers of allegiance to outdated grammar and style rules and on ways to stay current in language and technology. Saller's ideas struck a chord, and the little book with big advice quickly became a must-have reference for copy editors everywhere. In her search for practical strategies for keeping the peace, The Subversive Copy Editor was born. ![]() ![]() Saller realized that when these sides squared off, it was often the reader who lost. Longtime manuscript editor and Chicago Manual of Style guru Carol Fisher Saller has negotiated many a standoff between a writer and editor refusing to compromise on the "rights" and "wrongs" of prose styling. ![]() ![]() ![]() You might think from the title of Religion and the Decline of Magic that there is going to be some causal relationship between the two noun phrases: that this is a story of how religion grew as magic diminished.īut that is not at all the story being told in this fantastically wide-ranging, compendious study of the beliefs of sixteenth- and seventeenth-century England. He has published essays on many different aspects of the social and cultural history of early modern England. ![]() ![]() He has held visiting appointments at Princeton, Stanford, Columbia and Louisiana State Universities. Member of the American Academy of Arts and Sciences, and an Hon. He is a member of the Academia Europaea, a Founding Member of the Learned Society of Wales, a Foreign Hon. Elected FBA in 1979, he was President of the British Academy (1993-97). He is now an Honorary Fellow of All Souls, Balliol, Corpus Christi and St John's. He returned to All Souls as a Distinguished Fellow (2001-15). Antony's (1955), a Prize Fellow of All Souls (1955-57), Fellow and Tutor of St John's (1957-85), Reader (1978-85), ad hominem Professor (1986) and President of Corpus Christi (1986-2000). He has spent all his academic career in Oxford, as a senior scholar of St. Sir Keith Thomas was born in 1933 and educated at Barry County Grammar School and Balliol College, Oxford, where he read Modern History. ![]() ![]() ![]() ![]() This is not the only thing that makes me think HtRaB is more about being able to understand a book than understand the world, although it’s the only one I can articulate. ![]() This seems to me to be setting up both the author and the reader to throw out a lot of information because they weren’t expecting to see it or couldn’t fit it into their existing frameworks- reading like a state, in essence. What I can say is that it expects books to follow a rigid structure, and to have a single unifying point (what they call “the unity”). ![]() What subset, you might ask? I don’t have a great answer, because the authors clearly consider the subset to be the only books, or the only books worth reading, so they didn’t leave a lot of clues. It took me a long time to put my disappointment into words, but with the help of someone on Facebook I finally figured it out: How to Read a Book is aimed at a narrower subset of books than it acknowledges. How to Read a Book ( affiliate link) is generally very well regarded in this area and came with a strong recommendation from the CEO of Roam, who I would expect to have pretty good thoughts on learning structure. You might think I should have started with that, but it was useful to get a sense of what problems I needed to solve before I looked for the solution. As part of my research on how to bootstrap understanding in a field, I’m reading books that attempt to answer that question. ![]() ![]() ![]() That’s a long-winded way of saying the source novel is The Devil’s Own by Norah Lofts and it was adapted into the film The Witches by Hammer Film Productions in 1966. Just to muddy the waters further, the stated author, Peter Curtis, is not Peter Curtis at all, but the nom-de-plume of the historical fiction author, Norah Lofts. Having said that, if anyone out there can refute this and has a copy of the novel with the title Catch as Catch Can, then please do get in touch. Various online sources also state that it was published under the title of Catch as Catch Can but I can find no evidence of this at all and it just goes to show the dangers of people writing articles rehashed from Wikipedia entries. ![]() In 1970, Corgi published it with the title of The Little Wax Doll. Now, The Witches was the name given to the novel on the release of the film in 1966, it had the original title of The Devil’s Own. I will be discussing both the film and the novel in these articles and they will contain spoilers.įirst up, we have The Witches by Peter Curtis, first published in 1960. I have a fair few of these tie-ins on the shelves so I thought I’d perhaps share them here. We all love a film tie-in in the world of tawdry horror paperbacks, don’t we? Whether it’s a novelisation of the film or a re-issue of a novel with the artwork (and often the new name of) the film adaptation. ![]() ![]() But if proving her humanity means that she and Tyrus must do inhuman things, is the fight worth the cost of winning it? Excerpt She will have to prove the humanity that she’s found inside herself to the whole Empire-or she and Tyrus may lose more than just the throne. But she cannot protect him by being the killing machine she once was. He is the love of her life, and they are partners in this new beginning. The ruling class, the Grandiloquy, has held control over planets and systems for centuries-and they are plotting to stop this teenage Emperor and Nemesis, who is considered nothing more than a creature and certainly not worthy of being Empress. One where creatures like Nemesis will be given worth and recognition, where science and information can be shared with everyone and not just the elite.īut having power isn’t the same thing as keeping it, and change isn’t always welcome. Tyrus has ascended to the throne with Nemesis by his side and now they can find a new way forward-one where they don’t have to hide or scheme or kill. ![]() ![]() Kincaid’s New York Times bestselling novel, The Diabolic, which called “the perfect kind of high-pressure adventure.” ![]() ![]() ![]() A furious power ballad about never giving up, even in the face of overwhelming odds, We Sold Our Souls is an epic journey into the heart of a conspiracy-crazed, paranoid country that seems to have lost its very soul.where only a girl with a guitar can save us all. It's a journey that will take her from the Pennsylvania rust belt to a Satanic rehab center and finally to a Las Vegas music festival that's darker than any Mordor Tolkien could imagine. This revelation prompts Kris to hit the road, reunite with the rest of her bandmates, and confront the man who ruined her life. Everything changes when she discovers a shocking secret from her heavy metal past: Turns out that Terry's meteoric rise to success may have come at the price of Kris's very soul. ![]() He is the author of Horrorstör, My Best Friend’s Exorcism. ![]() Two decades later, former guitarist Kris Pulaski works as the night manager of a Best Western - she's tired, broke, and unhappy. Grady Hendrix Penguin Random House Grady Hendrix is an award-winning novelist and screenwriter living in New York City. New York Times bestselling author Grady Hendrix makes up lies and sells them to people. As usual, theres a lot of stuff to love, but I felt like this book just meandered a bit too much and never fully delivered on some of the ideas. In the 1990s, heavy metal band Dürt Würk was poised for breakout success - but then lead singer Terry Hunt embarked on a solo career and rocketed to stardom as Koffin, leaving his fellow bandmates to rot in rural Pennsylvania. Im a big fan of Grady Hendrix, and I enjoyed We Sold Our Souls well enough, but I think its the weakest of his works. ![]() ![]() ![]() Slate sends them on a mission to show some Neanderthals a night on the town in hopes of luring them into this new system of “working for a living” – in his quarry, of course! Find out what happens to Fred and the gang when they finally get to learn how Bedrock’s “one percent” lives in this satirical take on life in the world’s first civilization this summer! In this 40-page extra-sized premiere issue, fans will be introduced to the town of Bedrock, where Paleolithic humans dine on artisanal prepared mammoth after shopping at the Neandertall & Big Men’s Clothing stores, get the latest news via cave painting, and folks drive foot-powered cars. Writer Mark Russell (Prez) and artist Steve Pugh will bring readers their version of Fred, Wilma, Barney, Betty, Pebbles and Bamm-Bamm in the debut issue of The Flintstones, on sale July 6. ![]() |